Question
Human Glucose Transporters
Human glucose transporters (GLUTs) are membrane proteins responsible for the facilitated transport of glucose across the cell membrane. Glucose is a primary energy source for cells, and these transporters play a crucial role in maintaining glucose homeostasis in the body. There are different types of glucose transporters, each with specific tissue distributions and functions.
GLUTs are divided into several isoforms, numbered from GLUT1 to GLUT14. These isoforms vary in their affinity for glucose and their tissue localization. The most commonly studied GLUTs are GLUT1, GLUT2, GLUT3, and GLUT4, each with distinct physiological roles:
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