IGNOU MSTE 3 SOLVED ASSIGNMENT

Ques 1.

State whether the following statements are True or False. Give reason in support of your answer:

(a) Equality of slopes is the basic requirement for the parallel-line assay.

(b) The quantal assay is applicable when the response is the percentage of subjects who responded to a treatment at different doses.

(c) A complete life table is more elaborate than an abridged life table.

(d) Primary prevention includes strategies designed to reduce the incidence of disease.

(e) In Phase II of a clinical trial, we determine a safe dosage range and identify potential side effects.

Ques 2.

In a quantal assay, the number of cured cases for five doses of a standard and four doses of a new test drug are recorded in the following table:

Determine the median effective dose for the standard and test drugs using regression model.

Ques 3.

Write a short note on the Sampling Registration method of data collection for vital statistics.

Ques 4.

The number of births occurring in a country in 2015 classified according to age of mother, together with the female population in each group of the childbearing period, is given as follows:

The total population of the country in 2015 was 2285.8 thousand. Using the given information, determine the following:

(i) CBR,

(ii) GFR,

(iii) ASFR for the country in 1958.

Ques 5.

(a) In a hypothetical study, 10 patients with kidney disease were randomly assigned to receive two dialysis methods (A and B). 5 patients received Dialysis-A followed by Dialysis-B, and the remaining 5 received Dialysis-B followed by Dialysis-A. The kidney function scores of these patients are given as:

Test whether the mean score for dialysis-A is different from the mean score of dialysis-B, assuming no carry-over effect.

(b) Describe descriptive and analytic epidemiology.

Ques 6.

Explain any five types of biases in clinical trials.

Ques 7.

Differentiate between direct and indirect bioassays.

Ques 8.

Explain the steps taken for minimising bias in a research setup of a clinical trial.

Ques 9.

Define experimental and non-experimental studies.

Ques 10.

State whether the following statements are True or False. Give reason in support of your answer:

(a) Equality of slopes is the basic requirement for the parallel-line assay.

(b) The quantal assay is applicable when the response is the percentage of subjects who responded to a treatment at different doses.

(c) A complete life table is more elaborate than an abridged life table.

(d) Primary prevention includes strategies designed to reduce the incidence of disease.

(e) In Phase II of a clinical trial, we determine a safe dosage range and identify potential side effects.

Ques 11.

In a quantal assay, the number of cured cases for five doses of a standard and four doses of a new test drug are recorded in the following table:

Determine the median effective dose for the standard and test drugs using regression model.

Ques 12.

Write a short note on the Sampling Registration method of data collection for vital statistics.

Ques 13.

The number of births occurring in a country in 2015 classified according to age of mother, together with the female population in each group of the childbearing period, is given as follows:

The total population of the country in 2015 was 2285.8 thousand. Using the given information, determine the following:

(i) CBR,

(ii) GFR,

(iii) ASFR for the country in 1958.

Ques 14.

(a) In a hypothetical study, 10 patients with kidney disease were randomly assigned to receive two dialysis methods (A and B). 5 patients received Dialysis-A followed by Dialysis-B, and the remaining 5 received Dialysis-B followed by Dialysis-A. The kidney function scores of these patients are given as:

Test whether the mean score for dialysis-A is different from the mean score of dialysis-B, assuming no carry-over effect.

(b) Describe descriptive and analytic epidemiology.

Ques 15.

Explain any five types of biases in clinical trials.

Ques 16.

Differentiate between direct and indirect bioassays.

Ques 17.

Explain the steps taken for minimising bias in a research setup of a clinical trial.

Ques 18.

Define experimental and non-experimental studies.

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