IGNOU MCMM 1 SOLVED ASSIGNMENT 2024

Ques 1.

Describe in detail the sequence of events after an individual gets the HIV infection/ the HIV enters the body. Describe the factors that determine the progression of HIV infection.

Ques 2.

Describe the various models used for HIV estimation in India. Also discuss the HIV estimation and modelling process

Ques 3.

Discuss the molecular epidemiology of HIV.

Ques 4.

Enumerate various receptors and co-receptors involved in entry of HIV into the host cell

Ques 5.

Classify and list the types and sub types of HIV.

Ques 6.

Role of genetics in Drug Resistance.

Ques 7.

Describe the current global scenario of HIV/AIDS.

Ques 8.

Enumerate the different factors influencing disease progression in HIV infection.

Ques 9.

. Describe the relationship of CD4 count and opportunistic infections in HIV. Stage HIV infected patients based on presentation of OIs (opportunistic infections).

Ques 10.

A 24 yr old PLHIV presents with fever, weight loss (~ 20Kg) and painful deglutination. What WHO clinical stage of HIV infection is the patient in? Describe the differences between WHO clinical staging and CDC classification of HIV infection in adults.

Ques 11.

Discuss the various strategies of HIV testing

Ques 12.

Describe CD4 T cells and viral load testing as used in the National Programme

Ques 13.

Describe the various methods for HIV– DR testing.

Ques 14.

Discuss the diagnosis of HIV infections in children and infants below 18 months of age.

Ques 15.

Describe the common clinical manifestations of HIV infections in an adult.

Ques 16.

Discuss briefly WHO clinical staging of HIV disease in adults and adolescents.

Ques 17.

. List the upper and lower respiratory tract infections which can be seen in PLHIV. Describe the clinical features, diagnosis and treatment of bacterial pneumonia.

Ques 18.

A 30 year old male truck driver was admitted with history of fever and generalized headache for one month and altered sensorium for three days prior to admission. On examination the patient was drowsy, had neck rigidity, but there was no focal neuro deficit. He was found to be HIV +ve with a CD 4 count of 90 cells/mm3 . CSF examination showed budding yeast like structures.

Ques 19.

i) What is the diagnosis?

Ques 20.

ii) What tests will you do to confirm your diaganosis?

Ques 21.

iii) How do you treat this condition?

Ques 22.

iv) When will you start ART?

Ques 23.

v) How will you treat his headache?

Ques 24.

Adrenal gland involvement in HIV.

Ques 25.

Management of HIV/HBV co-infection.

Ques 26.

Approach to a PCHIV presenting with Anemia.

Ques 27.

AIDS defining cancers

Ques 28.

Common causes of fluid and electrolyte disturbances in HIV infection

Ques 29.

Complications of severe falciparum malaria

Ques 30.

Describe briefly the management of tuberculosis in HIV infected individuals.

Ques 31.

Enumerate the various dermatological disorders highly indicative of HIV infection & discuss the diagnosis & management of any one of them.

Ques 32.

Kaposi’s Sarcoma

Ques 33.

Etiolegy, diagnosis and management of Penicillosis

Ques 34.

Diagnosis of Tubercular Pericardial effusion.

Ques 35.

What are the three ‘I’ methods for reducing burden of Tuberculosis among HIV infected.

Ques 36.

Adverse effects of Anti Tubercular Treatment in HIV.

Ques 37.

Clinical features of Tuberculosis in children.

Ques 38.

What are Nucleoside Reverse Transcriptase Inhibitors (NRTI’s)? Discuss the mechanism of action, dosage and adverse effects of NRTIs used in the National Programme regimens.

Ques 39.

Describe the ART initiation (first line) guidelines under the NACP.

Ques 40.

Describe the adverse effects of Protease Inhibitors (PIs).

Ques 41.

Describe the ART- preparedness counseling.

Ques 42.

Discuss the mechanism to improve adherence to ART in PLHIV.

Ques 43.

Discuss the concepts of “Substitution” in First Line ART. Describe the substitutions done in the National Programme.

Ques 44.

Discuss the clinical and immunological monitoring of a patient on ART under the national programme.

Ques 45.

Define IRIS. Discuss the different categories of IRIS. Describe the causes of IRIS.

Ques 46.

. Discuss the role of the PPTCT programme in the National AIDS control programme : its concept, responsibilities and interventions

Ques 47.

ART is HIV – 2 infection.

Ques 48.

State AIDS clinical expert panel (SACEP) – roles, responsibilities, mechanism.

Ques 49.

Discuss the strategy to assess to risk of HIV transmission to a health care worker after a suspected exposure.

Ques 50.

Describe the indicators of programme monitoring at the ART centre level.

Ques 51.

Discuss the approach to ART modification is a PLHIV with known liver disease.

Ques 52.

Describe the national ART initiation guidelines for PLHIV with Hepatitis B and C co-infections.

Ques 53.

Discuss the concept of “continum of care” specifically in the context of women

Ques 54.

Describe the package of sexual and reproductive health for women living with HIV.

Ques 55.

Discuss common opportunistic infection in children.

Ques 56.

Describe the clinical and immunological criteria used for determining ART eligibility in children under the national programme.

Ques 57.

Describe the early warning signs of developmental delay in children.

Ques 58.

Discuss the behavior change models and theories.

Ques 59.

Describe the types of counseling in the national programme.

Ques 60.

Discuss the concept, mechanisms and challenges of Nutritional Supplementation in the national programme.

Ques 61.

Discuss HIV counseling in adolescents infected with HIV.

Ques 62.

Discuss the OP prophylaxis provided to children living with HIV infection.

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